Poobottle
Poobottles hover high above the ground, immune to attacks, and float towards any 
Poops within the room. Upon traveling over one, it will slam down into it to shoot out a ring of 8 projectiles and destroy the Poop. After slamming into the Poop they will be stunned on the ground and vulnerable to damage. Afterwards it flies up again becoming invulnerable once more. Poobottles are locked into their attack after starting it, and if the Poop is destroyed while they begin the slam, they will still slam into the ground, but there will be no additional effects.
If there are no Poops remaining in the room, they will float off-screen, and the room will be cleared if there are no other enemies left afterwards.
The projectiles created by Poobottles vary depending on the types of Poop they destroy. Any items spawned by Poops or effects activated upon their destruction will occur as they normally would.
- Brown Poop: Brown projectiles.
Corny Poop: Brown projectiles.
Red Poop: Pink-red projectiles.
- Red Poop does not damage Poobottle and may regenerate to be used by it multiple times.
Rainbow Poop: Rainbow projectiles.
Holy Poop: Spectral projectiles.
Black Poop: Black projectiles.
Gold Poop: Golden projectiles and coin projectiles.
Charming Poop: Brown projectiles
- When destroyed, Charmed Poops will spawn friendly
Dips that will immediately attack the Poobottle, sometimes killing it before it can retreat.
- When destroyed, Charmed Poops will spawn friendly
Giant Poop: Big brown projectiles that deal a full heart of damage.
Shampoo: Spawns 4 bubbles in diagonal directions which linger in the room.
Beehive: Orange projectiles.
Trashbag: Brown projectiles. Several random flies will spawn.
Nest: White projectiles.
Poison Poop: Brown projectiles.
Petrified Poop: Rock projectiles.
Cursed Poop: Bone projectiles or purple projectiles with a small aura that inflicts fear.
Evil Poop: Red projectiles with a small, pitch-black aura.
Platinum Poop: White projectiles or silver coin projectiles.
Variants
Drainfly
Drainflies are upgraded versions of Poobottles and behave similarly, but after their initial attack of 8 projectiles, they will latch onto their poop for a continuous period and spawn many projectiles and/or enemies around itself.
Like Poobottles, Drainflies will have special projectiles for each type of poop, along with other bonus effects. Their initial projectiles will be identical to Poobottles, but their special attack afterwards will be much more distinctive.
- Brown Poop: Spawns brown projectiles and Dips.
- Corny Poop: Spawns brown projectiles,
Corns and 
Attack Flies. - Red Poop: Spawns pink-red projectiles and
Spicy Dips. - Rainbow Poop: Spawns random projectiles and enemies from all other poop types.
- Holy Poop: Spawns spectral projectiles and
Spoops. - Black Poop: Spawns a puddle of black creep and
Blots. - Gold Poop: Spawns numerous golden and coin projectiles at a much faster rate.
- Charming Poop: Spawns brown projectiles and hostile Dips, along with friendly Dip familiars.
- The friendly Dips will attack either the Drainfly or the spawned Dips.
- Giant Poop: Spawns large brown projectiles that deal a full heart of damage and
Squirts. - Shampoo: Spawns bubbles and
Drops. - Beehive: Spawns orange projectiles and
Swarm Flies or 
Dart Flies. - Trashbag: Spawns brown projectiles and Dips.
- Nest: Spawns white projectiles and
Spiders, alongside creating a pool of white creep. - Poison Poop: Spawns brown projectiles and Dips. Several random flies will also spawn.
- Petrified Poop: Spawns rock projectiles and
Rock Spiders. - Cursed Poop: Spawns bone projectiles or purple projectiles with a small aura that inflicts fear. Also spawns regular Dips.
- Evil Poop: Spawns red projectiles with a small, pitch-black aura. Does not spawn any enemies.
- Platinum Poop: Spawns white projectiles or silver coin projectiles. Does not spawn any enemies but fires projectiles much more frequently than on any other poop.
Notes
- If encountered in Dross, Drainflies will spawn
Drips instead of Dips and 
Splurts instead of Squirts.
Trivia
- In the Afterbirth+ version of Fiend Folio, Drainflies spawned
Menaces instead of Spoops when breaking Holy Poop, as the latter was not within that version of the MOD. - Poobottle's name is based on the real-life Blue Bottle Fly.
Gallery
A Poobottle lying on the ground.
Poobottle's appearance in Dross.
A Drainfly lying on the ground.
Drainfly's appearance in Dross.
