Items

Items are an integral part of The Binding of Isaac. These collectibles are used to modify Isaac's attributes, grant or modify tear effects, and much more.

The Fiend Folio MOD presents a wide range of items to collect and help Isaac battle against the onslaught of new foes! There's delicious corn, supportive friends, and even some cool sunglasses!

Fiend Folio: Reheated adds 159+ items overall, separated into 113 passive items and 46 active items.

This page is about Items added in Fiend Folio. More information about Items in general can be found in the vanilla page.

Active Items

Name	Icon	Flavor Text	Description	Quality
The Fiend Folio		Summon fiendish friends	Summons one of Fiend Folio's bosses or enemies to assist Isaac in the room.	2
D2		Throwable reroll	Can be thrown and will spin on the floor temporarily. Any pickups, enemies, and tears that pass through the D2 will be rerolled.	1
Store Whistle		Portable shop	Spawns a Shop Chest.	4
Risk's Reward		Psionic reroll. Quality up	Can be used to reroll an item in the Treasure Room to one of a higher quality. This is achieved by traversing a unique Psionic Cluster and fighting the Hermit.	3
Alpha Coin		Learn to use it!	Does a variety of effects based on the current room and exploration.	1
IPad		please...	Upon use, teleports every entity downwards towards the bottom of the room. This item does not appear in any item pools.	4
Golem's Rock		Trinket grinder	Spawns a random rock trinket the first time it's picked up. On use, grinds Isaac's current held trinket into a random rock trinket.	3
Grappling Hook		Get away from danger	Throwable hook that can be used to quickly travel. Can be used to climb onto Rocks. Isaac can take damage by falling into pits.	1
Golden Frog Head		Gas Is Good	Forces Isaac to stand still while used. Letting go makes Isaac fart, the fart getting more powerful the longer it is held down.	1
Sanguine Hook		This doesn’t belong to you	Throwable hook that latches onto and pulls in enemies and pickups. Enemies become bruised while hooked. Releasing enemies makes them hemorrhage and launch bloody tears towards Isaac that hurt other enemies.	3
Fiddle Cube		The Devil finds work for idle hands	Grants an increasing boost to damage and tears when used rhythmically. Damage and tears boost gradually dissipate while the item is not being used.	3
A.V.G.M.		Get Hooked	Pays out with Pennies and other potential prizes after using an increasing amount of times.	2
Malice		Concentrated hatred	Upon use, turns Isaac into a black fireball which charges across the room. This gives invulnerability, deals damage to enemies hit, and leaves a trail of black creep during the charge.	3
Contraband		Payment rendered on delivery	Acquired from Fake Beggars that look like ordinary Beggars, but drop this item and disappear when interacted with. On use, becomes consumed and applies several stacks of the Wavy Cap effect, heavily distorting the screen. If carried to the next floor, a Dealer will appear in the starting room and exchange it for 2-3 items from the Drug Dealer item pool.	0
Bedtime Story		Ready for bed	Makes all enemies in the room drowsy. Drowsy enemies will slow down and eventually fall asleep. Damaging a sleeping enemy deals double damage, but wakes them up.	2
Eternal D12		???	Switches into one of two modes when used. With a charge capacity of 2, has a high chance to reroll obstacles and a low chance to delete them. With a charge capacity of 1, has a low chance to reroll obstacles and a high chance to delete them.	2
Purple Putty		Reusable genetic modification	+1 Immoral Heart on use.	4
Fiend Mix		Making friends	On use, transforms half of Isaac's health into Minions. Upon clearing a room, Minions transform back into their respective Hearts as pickups.	2
White Pepper		Radial ghost fire	On use, shoots 5 flames in a ring around Isaac.	1
Perfectly Generic Object		Object Mimic	Copies the effects of Isaac's held pocket object (excluding cards, pills and runes). Drops one random object the first time it's picked up. Variable recharge time based on which object is used.	2
Wrong Warp		Sequence break	On use, teleports Isaac to a random floor. Chosen floor can be anywhere in the game, with no regard to current run progression.	3
Golden Plum Flute		Play time!	Summons Golden Plum to fight for Isaac in the current room.	2
Dogboard		Walk the dog!	While held, causes the player to continuously slide forward on the Dogboard. Activating Dogboard makes Isaac jump. This item is not in any item pool and is set to be hidden from appearing anywhere in a run.	0
Eternal D10		???	Rerolls enemies in the current room. Enemies rerolled have a 1/3 chance to disappear.	2
Toy Camera		Photographic genius!	Create a camera flash that destroys projectiles and confuses enemies. Grants a tears up if Isaac is caught in the flash. If enough enemies are caught in the flash, spawns a Cool Photo.	2
The Brown Horn		Unload their bowels	On use, causes all enemies to defecate violently, pushing them away from Isaac and spawning Dirty Mind Dips.	2
Eternal Clicker		???	Has a 50/50 chance to transform Isaac into a random character while removing the last item collected, or delete the player's character and all their held items from the run. This item does not appear in any item pools.	0
Snow Globe		Shakes Rocks	On use, causes an earthquake that displaces all Rocks, Poops, and Metal Blocks in the room.	2
Cherry Bomb		Baby boom	On use, Isaac picks up a small red bomb that can be thrown. The bomb's explosion deals no damage to Isaac and can't break Rocks.	2
Astropulvis		Supernova	On use, destroys the closest Rock and turns it into a large ghost. Using the item again will detonate all large ghosts in the room.	3
Azurite Spindown		-1	On use, rerolls all trinkets in the room by subtracting their internal ID number by 1.	3
King Worm		Temporary worm powers	On use, grants the effects of a random worm trinket for the current room. These effects can stack with multiple uses, including the effects of the same worm.	1
Dazzling Slot		Bring out inner greed	Pay 5 cents to turn an enemy into a one-time use Golden Slot Machine.	3
Kalu's Severed Head		Horrifying visage	Is held above Isaac's head, and controls a cone of vision. Enemies in the cone are petrified and take a minor amount of damage. Enemies killed while petrified burst into a ring of 8 tears.	2
Rat Poison		Skip all their rooms	When used in a room with a visible creator, skips it, and removes all future rooms by that person in the current run. The name of the creator is shown at the bottom of the screen if the "Room Names" option is enabled.	4
Angelic Lyre		Play a different tune	Rotates between 3 different "tunes" that passively change Isaac's tears into three different attack modes with their own stats and modifiers.	2
Horse Paste		Keep it together	Removes 1 Broken Heart. Can only be obtained as China with Birthright.	2
Lemon Mishuh???		Ranged mishap	Can be thrown in a given direction, creating a puddle of yellow creep on impact.	1
Nil Pasta		Spaghetti code	Captures up to 5 enemies with spaghetti ropes and holds them in place. Pulling out the spaghetti also removes parts of the enemies' code, causing them to become glitched and constantly take damage over time. Glitched enemies will occasionally lose their AI, sometimes replacing their behavior with that of Poople.	1
Empty Book		Write your own story!	Customizable active item. Does a variety of effects depending on what the player chooses.	1
Yick Heart		Reusable Malignancy	+1 Morbid Heart on use.	4
Gamma Gloves		Hulk out!	Creates a small shockwave around Isaac, pushing nearby enemies away.	1
Shredder		Item recycler	Converts all non-purchasable items in the room into an assortment of random pickups.	2
Loaded D6		Repeat your destiny	Rerolls all items in the room into items that Isaac already has. Cannot reroll items into those that would be useless when duplicated, unless Isaac has no other valid item.	4
Torture Cookie		Reusable torture	Hurts Isaac for a Half Red Heart of health. Either displays an evil fortune, spawns a Black Heart, spawns a random Reversed Major Arcana Card, or spawns an evil-themed trinket.	1
Dusty D10		Ol' unreliable	Rerolls all enemies in the room into random enemies from anywhere in the game. Enemies are attempted to be rerolled into ones with similar maximum HP.	0
Hedonist's Cookbook		Natural harvest	Causes all enemies with the lowest maximum HP in the room to explode in a shower of tears.	2
Error's Crazy Slots		Roll for your destiny	On use, a three-number slot appears above Isaac's head; using the item again locks in a number, and the slots will spin faster each time. Once all three numbers are locked in, the player is granted the item of the ID shown by the three numbers. If the item ID is invalid, Isaac will be teleported to the I AM ERROR Room.	4
Sculpted Pepper		Strength in arrogance	Spawns a stone block on use. Attacking the stone block chisels it. Fully chiseled stone blocks produce an aura that gives status effects to enemies and buffs to Isaac, with the types of effects differing with the appearance of the statue.	3

Passive Items

Name	Icon	Flavor Text	Description	Quality
Pyromancy		Double Tap Fireballs	Isaac periodically creates orbital fireballs, up to three. Double-tapping the shoot button launches a fireball, leaving a trail of flames and exploding on contact.	3
Dice Bag		Gives dice	Spawns a sack familiar that follows Isaac and drops a random Glass Dice after every 8 rooms cleared. Glass Dice mimic their respective Dice collectible and break after use.	3
Lil Fiend		Your own little bastard	Spawns a familiar that flies diagonally across the room and has a chance to spawn an Evil Hollow Minion when colliding with an enemy or enemy projectile. Evil Hollow Minions disappear on room clear and will not drop a Black Heart.	0
Baby Crater		Spiral shot buddy	Whilst Isaac is firing tears, Baby Crater creates a ring of tears around itself, similar to the enemy Craterface. Tears are released outwards when Isaac stops firing.	2
Mrs. Spooter		Turret pursuer	Spawns a blue Spooter familiar that pursues enemies and periodically fires tears.	1
Randy The Snail		Ricochet buddy	Snail familiar that retracts into its shell when hit by a projectile or walked into by Isaac, and will bounce around the room. Deals damage to enemies when bouncing into them.	1
Corn Kernel		Gotta mern 'em all!	Spawns a familiar that levels up when gaining multiple copies of this item: Level 1: Wavy Orbital. Level 2: Orbital that shoots weak explosions. Level 3: Familiar that teleports and chases enemies. Level 4: Familiar that teleports and lobs explosive corn.	2
GMO Corn		The devil's harvest	Isaac is immobilized and forced to consume 7 random pills. +1 Red Heart container. +1 damage.	2
Cool Sunglasses		Gold rush	+6 coins. Upon entering an uncleared room, 3 Pennies are taken from Isaac and strewn across the room. Walking near coins on the ground grants a speed up based on the distance to the coin. Collecting coins damages all enemies in the room.	2
Fiend's Horn		There's a bit of him in all of us	Enemies have a chance to spawn a Evil Hollow Minion on death. Evil Hollow Minions disappear on room clear and will not drop a Black Heart. Chance starts at 20% and scales to 35% at 14 luck. A bonus +2.5% chance is applied for every Immoral Heart Isaac has in his Health bar.	2
Spare Ribs		Return to sender	+1 Bone Heart. Taking damage fires out rib projectiles that circle around Isaac. Rib projectiles return to sender and are destroyed only on contact with what fired them. Rib projectiles can destroy enemy projectiles.	2
Bacon Grease		Empty calories	+1 empty Red Heart container. +0.15 shot speed. Empties 1 additional Red Heart container.	0
Devil's Umbrella		Hard to clean	+1 Half Soul Heart. Shooting tears has a chance to create a flurry of weak tears that leave yellow creep.	3
Nugget Bombs		Friends inside +5 bombs	+5 Bombs. Bombs spawn a Brown Nugget turret fly familiar when they explode. Turret flies gain unique effects when combined with other bomb upgrade Items.	1
Bee Skin		Buzz buzz	Every tear fired triggers 3 weaker tears spread around Isaac at equal angles. Each time this effect triggers, the angle of all tears is incremented clockwise.	3
Planet Badge		Welcome to Space camp!	+0.1 damage. Can only be obtained by using Chaos Card on The Sun.	4
Haunted Badge		You got the power pellet!	+0.1 damage. Can only be obtained by killing The Organization while under the effect of The Gamekid or Power Pill!.	4
Baby Badge		Take care of it!	+0.1 damage. Can only be obtained by killing Battie with The Fiend Folio.	4
Commissioned Badge		This thing cost 50 dollars	+0.1 damage. Can only be obtained by using Defuse on Buster when he's about to blow up after dying.	4
Dripping Badge		Ahaha, sure is sweaty in here	+0.1 damage. Can only be obtained by using Flush! on Monsoon while he is in his small form.	4
Mystery Badge		What's inside...?	+0.1 damage. Can only be obtained by landing the finishing blow on Buck with the swipe of Bag of Crafting.	4
Spatula Badge		Throw 'em on the griddle!	+0.1 damage. Can only be obtained by killing Griddle Horn with White Pepper.	4
Your Eternal Reward		You got all the badges!	+0.1 damage. Can only be obtained by getting all other Badges.	4
Pinhead		Sewing Shot	Luck-based chance to shoot sewing needles that pierce and inflict enemies with sewn. Sewn enemies link damage taken onto all other enemies with sewn.	3
Lil Lamb		Pretends to like you	Spawns a familiar that charges to shoot an Ipecac projectile. When Isaac takes damage, has a chance to drop to the floor and target enemies automatically.	3
Grabber		Throws Hands	Spawns a familiar based on Grabber from hit video game Grabber. Mirrors Isaac's movements and grabs things in front of them.	1
Imp Soda		Critical spit	Grants a chance that scales with luck to shoot critical tears that deal quintuple Isaac's damage.	3
Dad's Wallet		Damage debt	Shop items can be purchased when they are not affordable, with the amount owed accumulating as debt. Debt gives a multiplicative damage down. Debt can be reduced by picking up coins. Drops a Credit Card upon being picked up.	2
Beginner's Luck		Dwindles with time	+5 luck. −0.5 luck per how many floors down Isaac is. At minimum will grant +1 luck.	3
Dichromatic Butterfly		Hitbox down, Graze and Homing Amulet	Isaac's hitbox size is reduced and indicated by a red marker over top of him. +0.2 damage for the current room when narrowly avoiding a projectile. Caps at +3 damage. Luck-affected chance to fire a tear with 1.25× damage and aggressive homing.	3
Slippy's Guts		Distance	Enemies have a chance to spawn a lingering poison fart cloud on death. The chance scales with Isaac's luck, and is proportional to the enemy's maximum health. Isaac's Bombs spawn a lingering poison fart cloud after exploding.	1
Slippy's Heart		Intimacy	Chance to fart while near enemies. Farts vary in type and strength. Fart chance scales with luck.	1
Community Achievement		Proficiency in counting	+2.71 flat damage. Damage boost is based on the current records in the Fiend Folio Cornmunity Discord server's counting channels.	3
Chirumiru		HP + DMG Up, Perfect Freeze	+1 Soul Heart. +0.9 flat damage. Upon entering a room, all enemies are petrified for 0.9 seconds.	4
Golem's Orb		Lost and Found...	+2 Soul Hearts. +0.23 shot speed. +0.2 speed. +1 luck.	3
Leftover Takeout		All stats up, fortune up	+0.3 speed. 1.1× fire rate. 1.5× damage. +1.5 range. +1 luck. Luck-affected chance to fire a fortune cookie tear that deals 5% more damage and display a fortune upon hitting an enemy.	4
Modern Ouroboros		Voice like the devil	Tears leave oil creep upon impact. Walking over oil creep will ignite it.	3
Peach Creep		Creepy friend	Spawns a friendly Wall Creep familiar that tries to line up with enemies and shoots barrages of tears.	1
Gorgoneion		They're shy	Spawns a stationary familiar that gazes at enemies in the room, petrifying them as long as they are in its sight.	3
Ophiuchus		Serpent Bearer	Wiggly snake familiar that chases after enemies, poisoning them and dealing damage on contact. Prioritizes chasing after enemies that are not currently afflicted with Poison.	3
Cetus		Blowhole retaliation	Taking damage causes Isaac to spew out a large amount of tears that leave creep.	1
Deimos		Lifelong partner	Spawns a familiar that fires hooks that latch onto and pull enemies/pickups. Remains stationary while pulling in enemies/pickups. Inflicts enemies with bruising while hooked. On releasing enemies, inflicts them with hemorrhaging and fires blood tears in the direction they were released.	3
Pet Rock		Movable cover	Spawns a pet rock familiar that can be pushed around and block shots. Fills pits when pushed into them.	0
Birthday Gift		Careful what you wish for	Replaces all newly encountered collectibles with Mystery Gift. Rerolls and special/fixed drops are not affected.	4
Black Lantern		Silver-Lined Curses	+1 Black Heart. Guarantees a curse on every floor. Replaces curses with special new types of potentially beneficial curses.	2
Clear Case		Pocket active room	The next active item that is picked up will be assigned to the player's pocket slot.	2
Crucifix		For your sins, they die	Enemies killed by tears will leave behind a short-lived ghost with an aura. Standing in the aura grants a boost to tear rate and damage, and makes Isaac's tears homing.	3
Prank Cookie		Tastes like corn	Grants multi-colored tears with different status effects added in Fiend Folio.	3
The Devil's Harvest		Genetically modified revive	Upon death, respawn as Fiend.	2
Rubber Bullets		Bruising Tears	Luck-based chance to fire bullet tears that bruise enemies. Bruised enemies take bonus damage from all sources of damage based on the number of stacks applied.	3
The Deluxe		Every condiment	+1 Bone Heart. +1 Morbid Heart. +1 Gold Heart. +1 Eternal Heart.	2
Lil Minx		Double-tap possesser	Spawns a pink Menace familiar that charges at enemies. Double-tapping the shoot button will have Lil Minx possess the nearest enemy and inflict them with berserk. Double-tapping the shoot button again will have Lil Minx exit the enemy and launch a spectral tear barrage. Berserked enemies periodically switch targets between Isaac and other enemies, deal and take bonus damage, move faster, and cannot die during the duration.	3
Fetal Fiend		Bountiful	+1.4 damage. Converts all Red Hearts, Soul Hearts and Black Hearts to Immoral Hearts. Red Hearts are converted at a 2:1 ratio.	3
Secret Stash		...That’s right, they’re not gone!	On pickup, spawns a coin, a bomb, a key, and a random card/pill/rune/object. At the start of the next run, spawn 10% of the coins, keys, and bombs Isaac held at the end of the run (rounded down, max of 5) and any pocket consumables they held.	2
Glizzy		Hunger down	+1 half-filled Red Heart container. +0.1 speed. +0.1 flat fire rate. +0.1 flat damage. +0.1 range. +0.1 shot speed. +0.1 luck.	2
>3		HP up?	+3 Immoral Hearts.	2
Devilled Egg		Tears up + immorality	+2 Immoral Hearts. +0.3 tears.	2
Tea		HP up	+1 Red Heart container.	1
Fraudulent Fungus		Some stats up	+1 empty Red Heart container. +1 Rotten Heart. +0.20 speed. +0.30 damage. +2.50 range.	2
The Small Pipe		Congratulations on the pipe!	+1 Soul Heart. +0.2 damage. +0.2 tears. +0.2 shot speed. +0.2 speed.	2
The Small Wood		Tears up	+1 tears. +0.2 damage. −0.2 shot speed.	3
Peppermint		It burns! Wait, no it doesn't...	Chance to fire a flame that damages and slows enemies, and freezes them into ice statues on death.	2
Black Moon		It all returns to nothing	Isaac's tears gain a dark red glow. Killing an enemy with these tears creates a glowing red cross that damages enemies in an area of effect. Enemies killed by the cross don't spawn another cross.	2
Page of Virtues		Your faith holds true	On pickup, spawns a random wisp. Whenever this wisp is destroyed, spawns a new random wisp.	2
Bridge Bombs		Pit-filling blast +5 bombs	+5 Bombs. Bombs fill pits when they explode.	1
Lawn Darts		Hemorrhaging tears	Luck-affected chance to fire tears that inflict enemies with hemorrhaging. Hemorrhaging enemies periodically take damage, spew blood tears randomly around themselves and leave blood creep on the ground that damages other enemies.	2
Toy Piano		Diabolus in musica	22% chance, scaling with luck, to fire tears that doom enemies. Doomed enemies gain a counter that goes down every time they take damage. Upon reaching zero the enemy takes 5× Isaac's damage and the effect is removed.	3
Hypno Ring		Drowsing tears	Luck-affected chance to fire tears that makes enemies drowsy. Drowsy enemies slowly fall asleep, moving and attacking increasingly slower over time. Sleeping enemies remain still until they awake. They take double damage while asleep, but will instantly wake up upon taking any damage.	2
Musca		Locust Bombs + Bug chaser	+3 Bombs. Bombs spawn Locusts when they explode. Enemies have a luck-based chance to spawn a random Harbinger Locust on death.	3
Model Rocket		Accelerating tears	+1.5 range. 2× shot speed multiplier. Tears accelerate from zero shot speed to normal shot speed on firing. Tears deal bonus damage based on their speed upon impact.	2
Sibling Syl		Friends 'till the end	Familiar that follows Isaac around, shooting tears that deal 4.75 Damage.	1
Greg The Egg		Full of surprises	Spawns an egg familiar that has a chance to drop a random pickup after clearing a room. After being shot at by projectiles, has a chance to crack open and spawn another familiar from the Baby Shop Item Pool.	2
Familiar Fly		Loved by many	Orbiting familiar that deals contact damage and blocks projectiles. Swells up when close to enemies, until exploding into a ring of 10 tears that can charm enemies. Respawns some time afterwards. Can charm Fly-related enemies in close proximity.	1
Monas Hieroglyphica		Unite the cosmos	Grants the effects of a random Planetarium item effect every floor.	3
Deadly Dose		Powerful pills, fatal addiction	On pickup, spawns a Cyanide Pill. Cyanide Pills provide an all stats up, but will start a death timer that will kill Isaac after 60 seconds. Taking a pill that isn't a Cyanide Pill will cure it, removing the stats and stopping the timer. Increases the chance for Pills to drop on room clear. Pills that drop while Isaac is not under the effect of a Cyanide Pill can be replaced with Cyanide Pills.	1
Dad's Postiche		It feels yicky	Chance to spawn Blue Skuzzes when shooting tears. Morbid Hearts have a slightly higher chance to appear.	3
Excelsior		Explosive actives	Using active items will release fireworks, based on the item's amount of charge. Fireworks will home in towards enemies and explode.	3
Griddle Corns		DMG Up + it's all burnt	+0.3 damage. +1 Half Black Heart. Spawns a Spicy Key and 3 friendly Coal Spiders on pickup.	2
Chaldean Axe		Cut them down!	Periodically fire a piercing axe towards the closest enemy. The axe boomerangs back shortly after launch.	3
Penny Roll		Monthly allowance	Spawns a penny-related trinket, a Golden Penny and 4 random coins.	2
Evil Sticker		Riskier pickups	Spawns 6 Cursed Pennies upon being picked up. Increases the chance for Immoral Hearts, Cursed Pennies, Dire Chests, Spicy Keys, and Copper Bombs to spawn.	0
Wimpy Bro		Haha whee!	Slammer familiar that jumps on enemies, dealing 5 damage.	2
Robo-Baby 3.0		It is now state-of-the-art	Familiar that moves diagonally towards the direction Isaac moves. On contact with enemies or enemy projectiles, will fire 8 Technology lasers around it.	0
Nyx		Cast	Grants 3 gems that can be cast while attacking, homing onto enemies to inflict damage and bruise them. Bruised enemies take bonus damage from all sources based on the number of stacks applied.	3
Telebombs		Swap the bomb! +5 bombs	+5 Bombs. A target follows behind Isaac with a delay. When placing a bomb, the player teleports back to the marker, and the bomb instantly explodes.	1
Dice Goblin		Object hoarder	Spawns 3 random objects on pickup. Spawns 1 random object at the start of each floor.	1
Spindle		More discs!	Spawns 3 random Trial Discs. Trial Discs grant the effects of 3-5 random passive items for 1 minute. Spawns a Trial Disc when first entering a Boss Room.	1
Devil's Dagger		With haste comes power	Isaac throws daggers alongside his tears. Enemies when killed drop gems that can power up the daggers.	3
Strange Red Object		It emanates naivety	+1 Red Heart container. +0.30 damage. +0.05 speed. +2 luck.	3
D3		Reroll tears	Orbital dice familiar that rerolls Isaac's tears. Wacky.	1
Emoji Glasses		It's lit	Isaac Fires emoji tears that each have a unique effect. Cycles through 3 different emojis at a time.	1
Sack of Keys?		The sack feels hot...	Spawns a sack familiar that follows Isaac and drops a Spicy Key after every 7 rooms cleared.	1
Heart of China		It's fragile	+1 empty Red Heart container. Overhealing with Red Hearts charges a special health bar. Filling this health bar grants an empty Red Heart container. The number of hearts needed to fill this special bar scales with how many Red Heart containers Isaac has.	3
Devil's Abacus		Learn to count!	Counting with Isaac's tears grants an increasing damage and tears up. To count, Isaac must fire X amount of tears and stop, with X increasing by 1 each time.	1
Ka Ching!		10 coins	+10 coins.	0
Chomp Chomp!		10 glizzies	Grants 10 copies of Glizzy.	4
Batoomkling!		10 keys	+10 keys.	1
Badump!		10 hearts	Heals Isaac for 10 Red Hearts.	0
Bzzt!		10 charges	Grants 10 pips of charge for Isaac's held active item.	0
Infinity Volt		Double tap cord	Double tap to link to an enemy with an extension cord. Linked enemies are charmed and continually generate arcs of electricity. After being linked for long enough, the enemy will explode.	2
Horncob		Reap what you sow	Isaac shoots pill tears that, upon killing an enemy, has a 25% chance for Isaac to take a random pill.	1
Mime Degree		...	Summons 3-5 translucent mime blocks in the room that blocks enemies and their projectiles. When Isaac touches a mime block, it will relocate to another place in the room.	1
Crazy Jackpot		Retributive gambling	On taking damage, Isaac rolls for a random positive effect. Effects can spawn coins or hearts, damage enemies, grant a random stat up, create a yellow creep puddle, or cause all effects at once.	1
Clutch's Curse		What if it was purple?	Familiar that possesses Isaac occasionally. When possessed, the next tear Isaac shoots will be a homing Ipecac tear. Rocks occasionally glow purple and create fire waves upon destruction.	2
Pet Peeve		Double-tap antipathy	Grudge familiar that moves around randomly and deals contact damage. Double-tapping a shoot button will have the familiar charge in that direction.	3
Mom's Stockings		Range up	+1.5 range. Spawns a bunch of Blue Skuzzes.	1
Golden Popsicle		Luck up	+1 Soul Heart. +2 luck. Spawns a random golden pickup.	2
Time Itself		Multi-euclidean tears	Has a chance to fire tears that cause enemies to become multi-euclidean. Multi-euclidean enemies can be shot through, doubling the tears.	3
Host on Toast		Damage + Range up	+0.5 damage. +1.5 range.	1
Bag of Bobbies		Gives bobby	Has a chance to spawn a Fragile Bobby familiar on room clear. Fragile Bobbies act similarly to Brother Bobby, but can die from taking enough damage from enemies.	3
Box Top		Luck up + redeemable prize	+2 luck. Spawns a Puzzle Piece.	1
Kinda Egg		HP up, don't swallow the prize!	+1 Red Heart container and heals for 1 Red Heart. Spawns a random object.	1
Dad's Dip		HP up...	+1 Red Heart container. +1 Morbid Heart.	1
Maria's Smash Trophy		It's the winner!	+1 damage. Enemies receive more knockback the less health they have.	2
Bottle of Water		Gulp it down!	+2 Soul Hearts. Gulps held trinkets on pickup. Spawns a random pill.	1
Fist Full of Ash		They hide poorly	+3 Bombs. More Tinted Rocks spawn on floors, and have odd, more obvious visuals. Breaking Tinted Rocks spawns a Half Red Heart, grants a fading Damage up, and a 50% chance of removing a Broken Heart. Isaac gains a Broken Heart upon entering a new floor.	3
Fiend's Third Leg		So full of leg	+3.33 damage. +1.5 tears. Tears become homing, leave a trail of damaging creep and create a Immoral Minion on impact. This item is not in any item pool and is set to be hidden from appearing anywhere in a run.	4
Isaac.chr		Backup character file	Upon death, Isaac respawns in the current room with randomized stats and health. Replaces some of Isaac's held items with TMTRAINER glitched items upon reviving.	0
Worm Insignia		The early worm catches the... wait...	+0.02 speed. Can only be obtained by using Eraser on Luncheon's Tapeworms to instantly end Luncheon's fight.	4
Dad's Battery		Energy debt	Allows Isaac to use their active item without having enough charge, resulting in gaining negative amount of charges. Having negative charge reduces Isaac's speed and shot speed. Negative charge persists after switching active items.	3
Isaac'D's Eulogy		Dicing with death	Killing an enemy has a luck-based chance to activate a random dice effect ( The D6, D20, etc.).	4
Brick Figure		Pick a brick	Spawns a Brick Separator and 4 Studs.	2
Goldshi Lunch		HP up, fast like a horse!	+1 Red Heart container and heals for 1 additional Red Heart. Grants +0.1 speed and +0.2 shot speed, which increases to +0.85 speed and +0.4 shot speed in cleared rooms.	2
Twinkle of Contagion		Take the Shot	Enemies have a chance to glow upon entering a room. Looking at a glowing enemy passes the effect onto Isaac, giving him a stat boost while under the effect. After a period of time, the glowing effect will jump from Isaac to a random enemy.	2
Token Bag		Gives tokens	Sack Familiar that drops a Token every 10 rooms. Tokens mimic the most recent pickup Isaac has collected.	4
Green Orange		May you attain enlightenment	+0.7 damage. +0.5 tears. Spawns a Soul Heart upon being picked up.	4
Reheated Pizza		Daily meal	+1 Red Heart container. At the start of each floor, spawns a random heart pickup.	2
Spelling Bee		Proficiency in spelling	Grants buffs to all applicable stats depending on the characters of the current seed. Tainted version of Community Achievement.	2
Too Many Options		There's just too many!	Special Room doors quickly cycle between 3 random types of Special Rooms until unlocked or entered.	3

Tainted Items

If the Tainted Treasure Rooms mod is installed, new items can appear in Tainted Treasure Rooms.

Name	Icon	Flavor Text	Description	Quality
Spelling Bee		Proficiency in spelling	Grants buffs to all applicable stats depending on the characters of the current seed. Tainted version of Community Achievement.	2

Trivia

• There were only 14 items added in the initial release of Fiend Folio for The Binding of Isaac: Afterbirth+.
• The Reheated Update added 124 items, not including trinkets.
• Two items were added in V2.4: Maria's Smash Trophy and Bottle of Water.
• One item was added in V2.6: Shredder.
• One item was added in V2.7: Fist Full of Ash.
• Eighteen items were added in V2.8: Loaded D6, Isaac.chr, Gamma Gloves, Dad's Battery, Torture Cookie, Isaac'D's Eulogy, Brick Figure, Goldshi Lunch, Twinkle of Contagion, Dusty D10, Token Bag, Green Orange, Reheated Pizza, Hedonist's Cookbook, Error's Crazy Slots, Sculpted Pepper, Too Many Options and Spelling Bee.