This article is actively being worked on.
When Isaac gives 
Contraband or 
Small Contraband to the 
Dealer, it will drop items from the Drug Dealer item pool. Items in this pool are themed around drugs, organs, weapons, explosives, cold hard cash, and other illicit goods.
Active Items
| Name
|
Icon
|
Weight
|
Description
|
| Kalu's Severed Head
|
|
1
|
- Is held above Isaac's head, and controls a cone of vision.
- Enemies in the cone are petrified and take a minor amount of damage.
- Enemies killed while petrified burst into a ring of 8 tears.
|
| Sanguine Hook
|
|
1
|
- Throwable hook that latches onto and pulls in enemies and pickups.
- Enemies become bruised while hooked.
- Releasing enemies makes them hemorrhage and launch bloody tears towards Isaac that hurt other enemies.
|
| Cherry Bomb
|
|
1
|
- On use, Isaac picks up a small red bomb that can be thrown.
- The bomb's explosion deals no damage to Isaac and can't break
 Rocks.
|
| Store Whistle
|
|
1
|
|
| Placebo
|
 
|
1
|
- Has the same effect as the pill currently held by Isaac.
- The charge time is based on the power of the pill.
|
| Forget Me Now
|
|
1
|
|
| Plan C
|
|
1
|
- Kills all enemies in the room, then kills Isaac three seconds later.
|
| Mom's Bottle of Pills
|
|
1
|
- On use, gives Isaac a random pill.
|
| Yuck Heart
|
|
1
|
|
| Razor Blade
|
|
1
|
- Takes one
 Red Heart of health and grants +1.2 damage for the current room.
- Repeated uses in the same room only take half a heart.
|
| Blood Rights
|
|
1
|
- Upon use, takes a full heart of health and deals 40 damage to all enemies in the room.
- Repeated uses in the same room only take half a heart.
|
| Scissors
|
|
1
|
- Turns Isaac's head into a stationary familiar for the current room which fires tears automatically.
- Isaac's body also shoots a controllable fountain of blood shots for the room.
|
| The Pinking Shears
|
|
1
|
- Separates Isaac's head from his body for the current room, granting flight and turning the body into a familiar that chases enemies.
|
| Potato Peeler
|
|
1
|
|
| Dark Arts
|
|
1
|
- Briefly grants +1 speed and makes Isaac invulnerable and intangible. When the effect ends, destroys all projectiles and damages all enemies Isaac ran through.
|
| Dull Razor
|
|
1
|
- Hurts Isaac without depleting health, activating any items that trigger upon taking damage.
|
| Meat Cleaver
|
|
1
|
- Splits all enemies in the room into two smaller versions of themselves with much less health.
|
| Remote Detonator
|
|
1
|
- Bombs placed by Isaac only explode when Remote Detonator is used. Gives 5 bombs.
|
| Kamikaze!
|
|
1
|
- Creates an explosion around Isaac, damaging him and nearby enemies as well as destroying obstacles.
|
| The Necronomicon
|
|
1
|
- Deals 40 damage to every enemy in the room.
|
| Anarchist Cookbook
|
|
1
|
|
| Book of Secrets
|
|
1
|
|
| Satanic Bible
|
|
1
|
|
| Lemegeton
|
|
1
|
- Spawns a wisp representing a random passive item, which orbits Isaac but can be destroyed. While the wisp is alive, Isaac gains that item's effects. Generation uses the current room's item pool 25% of the time, otherwise a random pool.
|
| Crooked Penny
|
|
1
|
- Spawns a penny and has a 50% chance to double all items and pickups in the room. If the effect fails, the items and pickups disappear.
|
| Portable Slot
|
|
1
|
- Upon use, consumes 1 Penny and has a chance to drop a random pickup, like a Slot Machine.
|
| Magic Fingers
|
|
1
|
- Uses 1 Penny to deal damage to all enemies in the room.
- Damage dealt is twice Isaac's damage +10.
|
| Wooden Nickel
|
|
1
|
- When used, has a roughly 50% chance to drop a penny, nickel or dime.
|
| Coupon
|
|
1
|
|
| Keeper's Box
|
|
1
|
|
| Moving Box
|
|
1
|
|
| Mr. ME!
|
|
1
|
|
| IV Bag
|
|
1
|
|
| We Need to Go Deeper!
|
|
1
|
|
| Dad's Key
|
|
1
|
|
| Sharp Key
|
|
1
|
|
| Suplex!
|
|
1
|
|
| The Gamekid
|
|
1
|
|
Passive Items
| Name
|
Icon
|
Weight
|
Description
|
| Twinkle of Contagion
|
|
1
|
- Enemies have a chance to glow upon entering a room.
- Looking at a glowing enemy passes the effect onto Isaac, giving him a stat boost while under the effect.
- After a period of time, the glowing effect will jump from Isaac to a random enemy.
|
| Fraudulent Fungus
|
|
1
|
|
| GMO Corn
|
|
1
|
|
| Deadly Dose
|
|
1
|
- On pickup, spawns a
 Cyanide Pill.
- Cyanide Pills provide an all stats up, but will start a death timer that will kill Isaac after 60 seconds. Taking a pill that isn't a Cyanide Pill will cure it, removing the stats and stopping the timer.
- Increases the chance for Pills to drop on room clear.
- Pills that drop while Isaac is not under the effect of a Cyanide Pill can be replaced with Cyanide Pills.
|
| Slippy's Guts
|
|
1
|
- Enemies have a chance to spawn a lingering poison fart cloud on death. The chance scales with Isaac's luck, and is proportional to the enemy's maximum health.
- Isaac's
 Bombs spawn a lingering poison fart cloud after exploding.
|
| Slippy's Heart
|
|
1
|
- Chance to fart while near enemies. Farts vary in type and strength.
- Fart chance scales with luck.
|
| Nugget Bombs
|
|
1
|
- +5 Bombs.
- Bombs spawn a
 Brown Nugget turret fly familiar when they explode.
- Turret flies gain unique effects when combined with other bomb upgrade Items.
|
| Bridge Bombs
|
|
1
|
- +5 Bombs.
- Bombs fill pits when they explode.
|
| Telebombs
|
|
1
|
- +5 Bombs.
- A target follows behind Isaac with a delay.
- When placing a bomb, the player teleports back to the marker, and the bomb instantly explodes.
|
| Dad's Wallet
|
|
1
|
 Shop items can be purchased when they are not affordable, with the amount owed accumulating as debt.- Debt gives a multiplicative damage down.
- Debt can be reduced by picking up coins.
- Drops a
 Credit Card upon being picked up.
|
| Lawn Darts
|
|
1
|
- Luck-affected chance to fire tears that inflict enemies with hemorrhaging.
- Hemorrhaging enemies periodically take damage, spew blood tears randomly around themselves and leave blood creep on the ground that damages other enemies.
|
| Experimental Treatment
|
|
1
|
- Randomly increases 4 and decreases 2 of Isaac's stats.
|
| Growth Hormones
|
|
1
|
|
| Roid Rage
|
|
1
|
|
| Speed Ball
|
|
1
|
|
| Synthoil
|
|
1
|
|
| The Virus
|
|
1
|
- Inflicts poison on enemies that make contact with Isaac (48 dmg per second).
- Also lets Isaac deal contact damage to enemies (24 dmg every tick).
- +0.2 speed.
|
| Adrenaline
|
|
1
|
|
| Euthanasia
|
|
1
|
|
| Blue Cap
|
|
1
|
|
| Magic Mushroom
|
|
1
|
|
| Mini Mush
|
|
1
|
|
| Odd Mushroom
|
|
1
|
|
| Odd Mushroom
|
|
1
|
|
| 1up!
|
|
1
|
|
| God's Flesh
|
|
1
|
|
| Mom's Coin Purse
|
|
1
|
|
| PHD
|
|
1
|
|
| False PHD
|
|
1
|
|
| Little Baggy
|
|
1
|
|
| Magic Scab
|
|
1
|
|
| Bob's Brain
|
|
1
|
|
| Isaac's Heart
|
|
1
|
|
| Akeldama
|
|
1
|
|
| Mystery Egg
|
|
1
|
|
| Stem Cells
|
|
1
|
|
| Raw Liver
|
|
1
|
|
| Giant Cell
|
|
1
|
|
| Mom's Knife
|
|
1
|
|
| Sacrificial Dagger
|
|
1
|
|
| Tough Love
|
|
1
|
|
| Hot Bombs
|
|
1
|
|
| Scatter Bombs
|
|
1
|
|
| Boom!
|
|
1
|
|
| Mr. Mega
|
|
1
|
|
| Rocket in a Jar
|
|
1
|
|
| Epic Fetus
|
|
1
|
|
| Dr. Fetus
|
|
1
|
|
| Pyromaniac
|
|
1
|
|
| Ouija Board
|
|
1
|
|
| Missing Page 2
|
|
1
|
|
| A Dollar
|
|
1
|
|
| Steam Sale
|
|
1
|
|
| A Quarter
|
|
1
|
|
| Sack of Pennies
|
|
1
|
|
| Piggy Bank
|
|
1
|
|
| Money = Power
|
|
1
|
|
| Deep Pockets
|
|
1
|
|
| A Pound of Flesh
|
|
1
|
|
| Mom's Purse
|
|
1
|
|
| Strawman
|
|
1
|
|
| Member Card
|
|
1
|
|
| Birthright
|
|
1
|
|
| Box
|
|
1
|
|
| Blood Bag
|
|
1
|
|
| Evil Charm
|
|
1
|
|
| Lucky Foot
|
|
1
|
|
| Mom's Key
|
|
1
|
|
| Chemical Peel
|
|
1
|
|
| Mysterious Liquid
|
|
1
|
|
| Mom's Lipstick
|
|
1
|
|
| Chaos
|
|
1
|
|
Normal / Hard
Greed / Greedier
