Zodiac Beggars can pay out with items from the 
Planetarium item pool or one of the signs of the Zodiac.
| Name
|
Icon
|
Weight
|
Description
|
| Aquarius
|
|
1
|
- A trail of blue creep is left behind Isaac, which damages enemies.
- The creep inherits most of Isaac's tear effects, like homing, etc.
|
| Aries
|
|
1
|
- Running into enemies while at a high speed will deal damage.
- Prevents Isaac from taking contact damage while moving at high speed.
|
| Cancer
|
|
1
|
- Grants
 The Wafer effect for the current room after taking damage.
|
| Capricorn
|
|
1
|
|
| Gemini
|
|
1
|
- Spawns a conjoined familiar which chases enemies close to Isaac, dealing ~8 damage per second.
|
| Leo
|
|
1
|
- Isaac can destroy
 Rocks by walking into them.
|
| Libra
|
|
1
|
|
| Pisces
|
|
1
|
|
| Sagittarius
|
|
1
|
|
| Scorpio
|
|
1
|
- Isaac's tears inflict poison, dealing damage to enemies over time.
|
| Taurus
|
|
1
|
- Isaac builds speed while in a room with enemies. At max speed, he gains the
 My Little Unicorn effect for 5 seconds.
|
| Virgo
|
|
1
|
- Adds a chance to give a shield that nullifies all incoming damage for 10 seconds upon taking damage.
- Converts all bad pills into good pills.
|
| Zodiac
|
|
1
|
- Gives Isaac a random zodiac item effect that changes every floor.
|
| Cetus
|
|
1
|
- Taking damage causes Isaac to spew out a large amount of tears that leave creep.
|
| Ophiuchus
|
|
1
|
- Wiggly snake familiar that chases after enemies, poisoning them and dealing damage on contact.
- Prioritizes chasing after enemies that are not currently afflicted with Poison.
|
| Musca
|
|
1
|
- +3
 Bombs.
- Bombs spawn Locusts when they explode.
- Enemies have a luck-based chance to spawn a random Harbinger Locust on death.
|
Normal / Hard
Greed / Greedier
