Template:ItemPool/DireChest

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Name Icon Flavor Text Effect Quality
Purple Putty
Purple Putty.png
Reusable genetic modification +1 immoral heart on use 4
Fetal Fiend
Fetal Fiend.png
Bountiful Damage Up

On pickup, replaces all soul and black hearts with immoral hearts

On pickup replaces all red hearts with immoral hearts at a 2:1 ratio

3
Devilled Egg
Devils egg.png
Tears up + immorality +2 immoral hearts

+0.3 tears up

2
Fiend Mix
Fiend Mix.png
Making fiends On use, transforms half your health into Fiend minions 2
Evil Sticker
Evil Sticker.png
Riskier pickups Increases the chance for immoral hearts, cursed pennies, dire chests, spicy keys, and copper bombs to spawn 0
GMO Corn
GMO Corn.png
The Devil’s Harvest You are immobilized and forced to consume 7 random pills

+1 max hearts

+1 damage up

2
Lil Fiend
Lil Fiend.png
Your own little bastard Flies diagonally across the room and has a chance to drop a fiend minion when colliding with an enemy or enemy projectile

Minions disappear on hit and will not drop a black heart

0
Fiend's Horn
Fiend's Horn.png
There’s a bit of him in all of us Enemies have a chance to drop a fiend minion on death

Minions disappear on room clear

Chance starts at 5% and scales to 20% on 14 luck

A bonus chance is applied for any immoral hearts you have

2
The Devil's Harvest
The Devil's Harvest.png
Genetically modified revive When dead, respawn as Fiend 2
Sack of Keys?
Sack of Keys?.png
The sack feels hot… Sack familiar that spawns spicy keys 1
Ball of Tar
Ball of Tar.png
Sticky feet... Adds a chance to shoot slowing tears.

Isaac leaves a trail of slowing creep behind as he moves, impeding enemies' speed.

2
Malice
Malice.png
Concentrated hatred The player turns into a fireball that can charge into enemies

Enemies killed this way have the chance to drop half black hearts

3
Modern Ouroboros
Modernouroboros.png
Voice like the devil Tears leave oil creep upon impact

Walking over oil creep will ignite it

2
Horncob
Horncob.png
Reap what you sow Killing an enemy has a chance to take a pill 1
Heart of China
Heart of China.png
It’s fragile Overhealing charges a special health bar

Filling this health bar grants an empty heart container

The number of hearts in this special bar scales with how many hearts you have

The special health bar can be viewed by standing near a heart that will overheal you or by viewing the map

3
Rubber Bullets
Rubber bullets.png
Bruising Tears Luck-affected chance to fore bullet tears that inflict enemies with bruising

Bruised enemies take bonus damage from all sources of damage based on the number of stacks applied

3
Imp Soda
Imp Soda.png
Critical spit Luck affected chance to shoot crit tears that deal quintuple damage 3
Prank Cookie
Prank cookie.png
Tastes like corn Grants multi-colored tears with different effects (hemorrhaging, bruising, drowsing, sewing, critting, etc.) 3
Risk's Reward
Risk's Reward.png
Everything is crawling Can be used to reroll an item in the treasure room to one of a higher quality

This is achieved by traversing a unique psionic zone and fighting Hermit

3
Deadly Dose
Deadly dose.png
Powerful pills, fatal addiction Cyanide pills can appear, which provide a risky all stats up! 1
D2
D2.png
Throwable Reroll Can be thrown and will spin on the floor temporarily

Any pickups, enemies and tears touching it will be rerolled

2
Clutch's Curse
Clutch's Curse.png
What if it was purple? Familiar that possesses the player occasionally

When possessed, the player can fire a homing ipecac tear

Rocks occasionally glow purple and shoot fire on destruction

2