Name |
Icon |
Quote |
Description |
Quality
|
Booster Shot
|
|
Compounding tears
|
- -0.5 damage.
- Piercing tears.
- Each time a tear passes through an enemy, it gains x1.5 damage.
|
3
|
Lifeblood Syringe
|
|
Vital injection
|
- Grants 2 soul hearts on use.
- Can only be recharged by killing Lifeseed Spirits that may spawn on enemy death.
|
3
|
Death Cap
|
|
Strength through mithridatism
|
- Deals damage, grants a small all stats down, and adds +5% poison tear chance per use.
- On the 6th use, grants a large all stats up, and fully heals Isaac.
|
3
|
Devil's Tooth
|
|
Exsanguinating strength
|
- Chance to fire a tear that Icarus-style upgrades enemies.
- Upgraded enemies have their health halved.
|
2
|
Mom's Suppository
|
|
Damage up?
|
- Damage x1.5, then -2.
- Spawns 1-3 random pills on first pickup.
|
3
|
Everlasting Pill
|
|
Stat-alteration free
|
- Mimicks the effect of a random, non-stat altering pill.
|
1
|
Melatonin
|
|
Zzz...
|
- On use:
- Temporarily paralyses Isaac.
- Grants a tears up for the duration of the current room.
- Tears now apply a stacking slowness effect to enemies. After a few stacks, the enemy is Mom's Contacts-style frozen.
- While held, sleeping in a bed grants a heart container.
|
2
|
Bob's Heart
|
|
Volatile friend
|
- Grants a trailing familiar that poisons enemies on contact.
- Grants a second trailing familiar that explodes on contact with enemies and respawns after a few seconds.
|
0
|
Dead Lung
|
|
Coughing up blood
|
- +1 black heart.
- Spawn a large puddle of red creep when taking damage.
|
1
|
F.O.P.
|
|
Unbreakable
|
- Upon hitting 0hp, all empty heart containers are converted into bone hearts.
|
3
|
Heart Rupture
|
|
Bursting hearts!
|
- Enemies have a chance to launch a red heart pickup on death.
- The launched heart pickup can be caught to heal, but will splatter into a small creep puddle if left to hit the floor.
|
2
|
Hemorrhoid
|
|
Charged blood blast
|
- When Isaac stops firing, a blast of blood projectiles is released opposite his movement direction.
- Taking damage spawns a red poop.
|
2
|
Tool
|
|
Remember being born?
|
- Damage taken by enemies has a chance to be duplicated onto every other enemy in the room of the same type and variant.
|
3
|
Bone Saw
|
|
Time to lose your medical licence
|
- Instantly kills shopkeepers and organic beggars.
- Low chance to spawn a body-part themed item when butchering a beggar.
- All butchered entities spawn 2 bone orbitals.
|
3
|
Eternal Bombs
|
|
Cast the beast into a lake of fire
|
- +5 bombs.
- Bombs deal double damage to bosses.
|
3
|
Weltling Sac
|
|
Blood explosions
|
- +5 bombs.
- A ring of blood explosions erupt around bombs when they detonate.
- Enemy projectiles in range of the blood explosions are destroyed.
|
2
|
Snap Bang
|
|
Snap, crackle, pop
|
- On use plants a small explosive charge at Isaac's position.
- The landmine detonates on contact with enemies, dealing 10x player damage and confusing anything not killed.
|
2
|
Book of Mormon
|
|
Do you have a moment?
|
- On use is held above Isaac's head.
- While held fears enemies in a large aura.
|
1
|
Friend Folio
|
|
Rival chapter
|
- Temporarily grants a random Retribution familiar each room.
|
2
|
The Iliad
|
|
Achilles' wrath
|
- "Throwable" item that launches a wall of spears from behind the chosen direction.
|
2
|
The Odyssey
|
|
Poseidon's wrath
|
- On use:
- Chains enemies near Isaac with anchors.
- Breaks rocks in a similar radius.
- Spawns a large puddle of damaging blue creep at Isaac's position.
|
2
|
Coinflip
|
|
Ricoshot
|
- On use throws a spinning penny onto the ground and removes 1 coin.
- Spinning pennies can no ricochet tears directly into enemies with a 1.5x damage multiplier.
|
3
|
Defibrillator
|
|
Starting to see black
|
- Every other room, gain a 1.5x damage multiplier.
|
2
|
False Idol
|
|
An untrue faith
|
- Grants +10.9 luck for the duration of the current room.
|
3
|
Laughing Gas
|
|
Winners don't use drugs
|
|
2
|
Philosopher's Stone
|
|
Health of wealth
|
- +1 heart container.
- +3 golden hearts.
|
1
|
Milk of Baphomet
|
|
HP up, random on-hit effects
|
- +1 heart container.
- When taking damage, activates a random on-damage effect.
|
2
|
Bootlicker
|
|
It hurts so good
|
- +1 empty heart container.
- Until you beat the next available floor-boss:
- You can no longer pick up hearts.
- +0.25 damage permanently, for every time you take damage.
|
2
|
Monster Candy
|
|
Proof of evolution
|
- Throwable item that permanently charms, and Icarus-style upgrades the enemy it collides with.
- If the thrown item misses, it is dropped on the ground as a pill.
- When the pill is used, it fully heals all friendly monsters.
|
2
|