Familiars are small companions, usually generated by passive items, that follow and assist Isaac. Effects of familiars include (but are not limited to) pickup generation, shooting familiars that fire their own tears at enemies, and orbitals that act as projectile shields and/or deal contact damage.

Fiend Folio adds its own menagerie of friends to assist the player!

This page is about Familiars added in Fiend Folio. More information about Familiars in general can be found in the vanilla page.

Temporary Familiars

Minions

Various Minions

Minions, also sometimes known as "Fiendish Friends", are tiny imp-like familiars that chase enemies and deal a percentage of Isaac's damage on contact over time, with the tick rate of the damage scaling with Isaac's fire rate. Very rarely, a Minion can land a critical hit that deals 5× Isaac's damage, with the chance to deal a critical hit scaling with luck.

If the player has the ability to fly, then all Minions created by the player will sprout wings and fly over obstacles.

Minions are primarily spawned from Immoral Hearts or by Fiend, and there are several types: Immoral Minions and Evil Minions, as well as Hollow variants of both of the former types. When the room is cleared while Minions are active in the room, every Immoral and Evil Minion will disappear and leave a Heart pickup of its original type (with one exception).

Immoral Minions are purple minions created from Immoral Hearts, and each Immoral Minion deals 20% of the player's damage per tick.
- Immoral Hollow Minions are created from Half Immoral Hearts. They appear to be a melting version of regular Immoral Minions and behave identically, but will turn back into a Half Immoral Heart when the room is cleared.
Evil Minions are black minions created from Black Hearts only while playing as Fiend, and each Evil Minion deals 40% of the player's damage per tick and has a higher chance to land a critical hit.
- Evil Hollow Minions are created from Half Black Hearts only while playing as Fiend, and they appear to be a melting version of regular Evil Minions and behave identically. However, they will not turn back into a Half Black Heart when the room is cleared, and will instead disappear with a puff of black smoke.
Entering or teleporting to another room before the room is cleared will cause all Minions to be left behind — returning to the room will have them appear in their pickup form with the exception of Half Black Hearts, from where they were last located.
- Exiting the run and returning will also cause this to happen, though this will also apply to Minions that persist in cleared rooms.

Name	Icon	Flavor Text	Description	Quality
Fiend Mix		Making friends	On use, transforms half of Isaac's health into Minions. Upon clearing a room, Minions transform back into their respective Hearts as pickups.	2

Name	Icon	Flavor Text	Description	Quality
Fiend's Horn		There's a bit of him in all of us	Enemies have a chance to spawn a Evil Hollow Minion on death. Evil Hollow Minions disappear on room clear and will not drop a Black Heart. Chance starts at 20% and scales to 35% at 14 luck. A bonus +2.5% chance is applied for every Immoral Heart Isaac has in his Health bar.	2
Lil Fiend		Your own little bastard	Spawns a familiar that flies diagonally across the room and has a chance to spawn an Evil Hollow Minion when colliding with an enemy or enemy projectile. Evil Hollow Minions disappear on room clear and will not drop a Black Heart.	0

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Fiendish Amethyst		Fiends galore!	Normal	Fiendish	On entering an uncleared room, spawns four Amethyst Minions. Amethyst Minions disappear on room clear and will not drop a Heart.

Name	Icon	Mimic Charge	Flavor Text	Description
Soul of Fiend			"Strength in numbers"	Spawns 5-8 Hollow Minions and 0-2 Black Heart Minions. Hollow Minions disappear into a cloud of smoke on clearing the room, while Black Heart minions drop a Black Heart.

Note: Minions are unaffected by any familiar modifiers such as BFFS!.
Note: Lil Fiend, Fiend's Horn, Fiendish Amethyst, Imp-plosion, and the Curse of the Imp effect from Black Lantern will only create Evil Hollow Minions, meaning that they will not turn into Hearts when the room is cleared.
- The Minions created by Implosion and Fiendish Amethyst will have a unique appearance, but otherwise still behave like regular Evil Hollow Minions.
Note: Fiend Mix can create Minions and Hollow Minions of all other Heart types that turn back into their type of Heart pickup when the room is cleared. However, all of them deal the same damage and have the same chance to land a critical hit as Immoral Minions — with the exception of Black Hearts, which will behave exactly like Evil Minions and Evil Hollow Minions.
Note: Unlike Minions created from other sources, Minions spawned by Fiend Mix, Soul of Fiend, and the Curse of the Imp effect from Black Lantern will persist between each room entered if spawned inside of a room that is already cleared.
- Minions spawned from the Curse of the Imp effect will persist for the next 3 rooms cleared, while those created by Fiend Mix and Soul of Fiend will only persist until a single room is cleared.

Fragile Bobbies

Various Fragile Bobbies

Fragile Bobbies are familiars that act identically to Brother Bobby, but are able to take damage from enemies and their projectiles, and can be killed after taking enough damage.

They can come in various different shades of blue, and will have a random rate of fire between 0.5 seconds and 0.83 seconds, and random tear damage between 2.8 and 4.2.

There is no cap to the maximum number of Fragile Bobbies allowed on screen, and they will last for the entire run or until killed.

Fragile Bobbies are affected by BFFS!, which will increase their size and double both their damage and their health.

Name	Icon	Flavor Text	Description	Quality
Bag of Bobbies		Gives bobby	Has a chance to spawn a Fragile Bobby familiar on room clear. Fragile Bobbies act similarly to Brother Bobby, but can die from taking enough damage from enemies.	3

Name	Icon	Flavor Text	Description
Egg Penny		Wealth of progeny	Chance to spawn a Fragile Bobby on picking up a coin.

Blue Skuzzes

Blue Skuzzes are friendly versions of Skuzzes that act similarly to Blue Flies and Blue Spiders, hopping towards nearby enemies in the room and damaging them on contact before dying. Blue Skuzzes deal 3× Isaac's damage on contact, unlike Blue Flies and Blue Spiders which deal only 2× Isaac's damage.

Name	Icon	Flavor Text	Description	Quality
Dad's Postiche		It feels yicky	Chance to spawn Blue Skuzzes when shooting tears. Morbid Hearts have a slightly higher chance to appear.	3

Name	Icon	Flavor Text	Description
Fuzzy Penny		Wealth of fuzz	Spawns a Blue Skuzz when picking up a coin.

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Skuzz Fossil		Friend 'till the end, crush effect	Fossil	Rare	Spawns 2-3 Purple Fleas when entering a new uncleared room. Crush Effect: Spawns 5-7 Blue Skuzzes.

Fleas

Fleas are the Blue Skuzz equivalent of Locusts. They act identically to regular Blue Skuzzes, but sport a different color and inflict a special effect when they damage enemies, based on their color:

Orange Fleas will burn enemies on hit.
Cyan Fleas will create a ring of 8 tears that deal damage equal to Isaac's damage on hit.
Purple Fleas will leave behind a black creep puddle on hit.
Beige Fleas will charm enemies on hit.

Name	Flavor Text	Description
Flea Circus	Infested	20% chance to spawn a random Flea after killing an enemy.
Flea of Deluge	I bring Deluge	Spawns a Cyan Flea when entering a new room. Cyan Fleas create a ring of 8 tears on hit.
Flea of Meltdown	I bring Meltdown	Spawns an Orange Flea when entering a new room. Orange Fleas can burn enemies.
Flea of Pollution	I bring Pollution	Spawns a Purple Flea when entering a new room. Purple Fleas will leave behind a black creep puddle on hit.
Flea of Propaganda	I bring Propaganda	Spawns a Beige Flea when entering a new room. Beige Fleas will charm enemies on hit.

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Skuzz Fossil		Friend 'till the end, crush effect	Fossil	Rare	Spawns 2-3 Purple Fleas when entering a new uncleared room. Crush Effect: Spawns 5-7 Blue Skuzzes.

Dips

Bee Dip Familiar Spider Dip Familiar Drop Familiar Cursed Dip Familiar Evil Dip Familiar Platinum Dip Familiar Fuzzy Dip Familiar

Fiend Folio adds several new Dips for each type of new Poop that can be spawned by Dirty Mind.

Beehives create Bee Dips that have flight but greatly reduced health, typically dying in a single hit.
Trashbags create default Dips, as their interaction with Dirty Mind hasn't been coded as of version 2.7.
Nests create Spider Dips that attack enemies, slowing them down as well as spawning Blue Spiders when dealing damage.
Shampoo create friendly Drops that attack enemies by landing on them from above, much like a normal Drop.
Cursed Poops create Cursed Dips that have a fear aura, causing enemies who come too close to run away.
Evil Poops create Evil Dips that have a confusion aura, causing enemies to lose track of Isaac and be stunned.
Platinum Poops create Platinum Dips that martyrize enemies they deal lethal damage to, creating a ghost of them with a holy aura that increases Isaac's tears and damage when inside it, much like White Poop.
Fuzzy Poops create Fuzzy Dips that spawn a Blue Skuzz on death. This can only be encountered when playing as Tainted ???.
Obtaining Dad's Dip while having Dirty Mind will create a unique Dip familiar with a green cap, similar to that seen from the Dad's Wallet costume.

The addition of naturally-appearing Petrified Poop and Poison Poop as obstacles allows access to Stone Dips and Poison Dips with Dirty Mind, without needing Tainted ??? or IBS.

Clots

The two new types of hearts added in Fiend Folio, Immoral Hearts and Morbid Hearts, can be consumed by Sumptorium and turned into unique clot familiars.

Name	Appearance	Health	Damage	Effect
Immoral Clot		15	35%	4% chance to fire an Imp Soda critical tear which deals 2.1× Isaac's damage.
Morbid Clot		10	35%	10% chance to fire a Tough Love tooth tear which deals 1.1× Isaac's damage.

Wisps

Wisps are orbiting familiars primarily spawned by Book of Virtues. They orbit around Isaac, dealing contact damage and blocking projectiles, and most of the time fire projectiles in the direction Isaac fires in. Most active items in the game spawn a special wisp when used in conjunction with Book of Virtues.

Fiend Folio adds some unique wisps for the active items it adds when used with Book of Virtues.

Item	Wisp Appearance	Effects
Golem's Rock		Fires Terra tears. Tears deal varying damage and can break grid objects and open Secret Room entrances.
Sanguine Hook		Hooking into an enemy creates 4 wisps. Wisps do not fire tears, but deal heavy contact damage. Wisps disappear when unhooking an enemy.
Fiddle Cube		Creates a gray wisp every use. Wisps begin to disappear if the item is not used rhythmically.
A.V.G.M.		Lower health. Creates a wisp every time a payout is rewarded. Spawns a Lemegeton wisp when an item is rewarded.
Bedtime Story		Deals 1.5x damage. Wisps give the drowsy effect for 2 seconds to enemies that destroy it.
Purple Putty		Shoots tears that have a 4% chance to be critical tears that deal 5x damage. Wisps spawn a Hollow Minion when destroyed which lasts for one room.
Fiend Mix		Does not shoot tears. Wisps spawn a Hollow Minion when destroyed which lasts for the rest of the room.
White Pepper		Spawns 5 of The Candle wisps.
Perfectly Generic Object		Spawns a random object when destroyed. Wisp tears have a 15% chance to drop a random object when killing an enemy.
Eternal D10		Wisp tears have a 10% chance to reroll enemies.
Eternal D12		Based on the item's charge, wisp tears have either a 1% or 5% chance to reroll rocks.
Cherry Bomb		Explodes at the same time as the Cherry Bomb, dealing 15 damage to enemies.
Astropulvis		Spawns a wisp whenever a ghost is detonated. The wisp is destroyed when another ghost is detonated, damaging enemies 3-4 times.
Angelic Lyre		Spawns a wisp corresponding to the color of the tune. Only one of these wisps can be active at a time. Wisps behave like regular wisps and all colors behave the same.
Lemon Mishuh???		Wisps occasionally create a small puddle of yellow creep underneath themselves.
Gamma Gloves		Does not shoot tears. Disappears after one second.
Shredder		Shoots Ouroboros Worm tears.
Dusty D10		Wisp tears have a 10% chance to reroll enemies.
Error's Crazy Slots		Creates a wisp each time a number is rolled. Wisps have high health and shoot Continuum tears.
IPad		Can only fire tears in the downward direction.

Vanilla Spawns

Fiend Folio adds a few collectibles and trinkets that spawn spider, fly, locust, and wisp familiars from the vanilla game.

Name	Icon	Flavor Text	Description	Quality
The Brown Horn		Unload their bowels	On use, causes all enemies to defecate violently, pushing them away from Isaac and spawning Dirty Mind Dips.	2

Name	Flavor Text	Description	Quality
Musca	Locust Bombs + Bug chaser	+3 Bombs. Bombs spawn Locusts when they explode. Enemies have a luck-based chance to spawn a random Harbinger Locust on death.	3
Nugget Bombs	Friends inside +5 bombs	+5 Bombs. Bombs spawn a Brown Nugget turret fly familiar when they explode. Turret flies gain unique effects when combined with other bomb upgrade Items.	1
Page of Virtues	Your faith holds true	On pickup, spawns a random wisp. Whenever this wisp is destroyed, spawns a new random wisp.	2

Name	Flavor Text	Rock Type	Rock Rarity	Description
Coprolite Fossil	Fecal artifact, crush effect	Fossil	Common	Spawns a Blue Fly when entering a new uncleared room. Crush Effect: Spawns 12 Blue Flies.
Fish Fossil	Wasteland king, crush effect	Fossil	Common	Spawns 1-4 Blue Flies when taking damage. Crush Effect: Spawns a friendly Portal.
Fly Fossil	Friend 'till the end, crush effect	Fossil	Rare	Spawns a Yellow Locust when entering a new uncleared room. Crush Effect: Spawns a Pretty Fly familiar.

Chasing Familiars

Familiars in this category actively chase enemies, dealing contact damage, shooting at, or applying other effects to them.

Name	Flavor Text	Description	Quality
Corn Kernel	Gotta mern 'em all!	Spawns a familiar that levels up when gaining multiple copies of this item: Level 1: Wavy Orbital. Level 2: Orbital that shoots weak explosions. Level 3: Familiar that teleports and chases enemies. Level 4: Familiar that teleports and lobs explosive corn.	2
Lil Lamb	Pretends to like you	Spawns a familiar that charges to shoot an Ipecac projectile. When Isaac takes damage, has a chance to drop to the floor and target enemies automatically.	3
Mrs. Spooter	Turret pursuer	Spawns a blue Spooter familiar that pursues enemies and periodically fires tears.	1
Ophiuchus	Serpent Bearer	Wiggly snake familiar that chases after enemies, poisoning them and dealing damage on contact. Prioritizes chasing after enemies that are not currently afflicted with Poison.	3
Wimpy Bro	Haha whee!	Slammer familiar that jumps on enemies, dealing 5 damage.	2

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Lithopedian		A stoney of your own	Normal	Common	Spawns a Stoney familiar that pushes enemies around and blocks shots.

Note: Only the 3rd and 4th level of the Corn Kernel familiar will chase enemies.

Orbital Familiars

Familiars that orbit Isaac, absorbing enemy projectiles and dealing contact damage.

Name	Icon	Flavor Text	Description	Quality
Corn Kernel		Gotta mern 'em all!	Spawns a familiar that levels up when gaining multiple copies of this item: Level 1: Wavy Orbital. Level 2: Orbital that shoots weak explosions. Level 3: Familiar that teleports and chases enemies. Level 4: Familiar that teleports and lobs explosive corn.	2
Familiar Fly		Loved by many	Orbiting familiar that deals contact damage and blocks projectiles. Swells up when close to enemies, until exploding into a ring of 10 tears that can charm enemies. Respawns some time afterwards. Can charm Fly-related enemies in close proximity.	1

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Star Sapphire		Movement detector	Normal	Rare	Spawns an orbital familiar that wobbly points towards the nearest enemy or projectile, blocks shots and deals contact damage.

Note: Only the 1st and 2nd level of the Corn Kernel familiar will orbit Isaac.

Pickup Generation Familiars

Familiars that generate pickups when certain conditions are met.

Name	Flavor Text	Description	Quality
Dice Bag	Gives dice	Spawns a sack familiar that follows Isaac and drops a random Glass Dice after every 8 rooms cleared. Glass Dice mimic their respective Dice collectible and break after use.	3
Greg The Egg	Full of surprises	Spawns an egg familiar that has a chance to drop a random pickup after clearing a room. After being shot at by projectiles, has a chance to crack open and spawn another familiar from the Baby Shop Item Pool.	2
Sack of Keys?	The sack feels hot...	Spawns a sack familiar that follows Isaac and drops a Spicy Key after every 7 rooms cleared.	1
Token Bag	Gives tokens	Sack Familiar that drops a Token every 10 rooms. Tokens mimic the most recent pickup Isaac has collected.	4

Shooting Familiars

Familiars that attack with their own tears or other effects as long as Isaac is attacking or charging a shot.

Name	Flavor Text	Description	Quality
Baby Crater	Spiral shot buddy	Spawns a familiar that follows Isaac around the room. Whilst Isaac is firing tears, Baby Crater creates a ring of tears around itself, similar to the enemy Craterface. Tears are released outwards when Isaac stops firing.	2
Corn Kernel	Gotta mern 'em all!	Spawns a familiar that levels up when gaining multiple copies of this item: Level 1: Wavy Orbital. Level 2: Orbital that shoots weak explosions. Level 3: Familiar that teleports and chases enemies. Level 4: Familiar that teleports and lobs explosive corn.	2
Deimos	Lifelong partner	Spawns a familiar that fires hooks that latch onto and pull enemies/pickups. Remains stationary while pulling in enemies/pickups. Inflicts enemies with bruising while hooked. On releasing enemies, inflicts them with hemorrhaging and fires blood tears in the direction they were released.	3
Lil Lamb	Pretends to like you	Spawns a familiar that charges to shoot an Ipecac projectile. When Isaac takes damage, has a chance to drop to the floor and target enemies automatically.	3
Sibling Syl	Friends 'till the end	Familiar that follows Isaac around, shooting tears that deal 4.75 Damage.	1

Name	Icon	Flavor Text	Description
Hatred		Double tap distilled malice	Spawns a small black clot familiar next to Isaac that moves and shoots through his same inputs. The clot charges forwards when a shooting key is double-tapped, leaving a trail of black creep and respawning after hitting a wall.

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Fetal Stone		Prehistoric friend	Normal	Rare	Grants a rocky familiar that fires rock tears that have a chance to confuse enemies.

Note: Only the 2nd level of the Corn Kernel familiar will shoot projectiles when Isaac shoots.

Wandering Familiars

Familiars that move around the room sporadically.

Name	Flavor Text	Description	Quality
Greg The Egg	Full of surprises	Spawns an egg familiar that has a chance to drop a random pickup after clearing a room. After being shot at by projectiles, has a chance to crack open and spawn another familiar from the Baby Shop Item Pool.	2
Pet Peeve	Double-tap antipathy	Grudge familiar that moves around randomly and deals contact damage. Double-tapping a fire button will have the familiar charge in that direction.	3
Randy The Snail	Ricochet buddy	Snail familiar that retracts into its shell when hit by a projectile or walked into by Isaac, and will bounce around the room. Deals damage to enemies when bouncing into them.	1

Bouncing Familiars

Familiars that bounce around the room in a zig-zag pattern, changing directions when hitting a wall.

Name	Icon	Flavor Text	Description	Quality
Lil Fiend		Your own little bastard	Spawns a familiar that flies diagonally across the room and has a chance to spawn an Evil Hollow Minion when colliding with an enemy or enemy projectile. Evil Hollow Minions disappear on room clear and will not drop a Black Heart.	0
Robo-Baby 3.0		It is now state-of-the-art	Familiar that moves diagonally towards the direction Isaac moves. On contact with enemies or enemy projectiles, will fire 8 Technology lasers around it.	0

Name	Icon	Flavor Text	Rock Type	Rock Rarity	Description
Tiger's Eye		Stony gaze	Normal	Rare	Spawns a Tiger's Eye familiar that bounces around the room, dealing contact damage and blocking shots. Bounces directly towards the closest enemy when bouncing off a wall.

Others

Familiars that don't fit into any of the above categories or that produce multiple effects.

Name	Flavor Text	Description	Quality
Bag of Bobbies	Gives bobby	Has a chance to spawn a Fragile Bobby familiar on room clear. Fragile Bobbies act similarly to Brother Bobby, but can die from taking enough damage from enemies.	3
Clutch's Curse	What if it was purple?	Familiar that possesses Isaac occasionally. When possessed, the next tear Isaac shoots will be a homing Ipecac tear. Rocks occasionally glow purple and create fire waves upon destruction.	2
Gorgoneion	They're shy	Spawns a stationary familiar that gazes at enemies in the room, petrifying them as long as they are in its sight.	3
Grabber	Throws Hands	Spawns a familiar based on Grabber from the hit video game Grabber. Mirrors Isaac's movements and grabs things in front of them.	1
Lil Minx	Double-tap possesser	Spawns a pink Menace familiar that charges at enemies. Double-tapping the shoot button will have Lil Minx possess the nearest enemy and inflict them with berserk. Double-tapping the shoot button again will have Lil Minx exit the enemy and launch a spectral tear barrage. Berserked enemies periodically switch targets between Isaac and other enemies, deal and take bonus damage, move faster, and cannot die during the duration.	3
Peach Creep	Creepy friend	Spawns a friendly Wall Creep familiar that tries to line up with enemies and shoots barrages of tears.	1
Pet Rock	Movable cover	Spawns a pet rock familiar that can be pushed around and block shots. Fills pits when pushed into them.	0

Name	Icon	Flavor Text	Description
Grabber's Enemy		Caught you!	Flying Grabber hand familiars spawn that drag Isaac, pickups, and enemies around.

Name	Flavor Text	Rock Type	Rock Rarity	Description
Lost Artifact	Mew mew fairies	Normal	Fiendish	Upon clearing rooms, spawns a random amount of Fairy Fly familiars of different sizes. Fairy Flies deal contact damage to enemies, and die after some time.
Onion Rock	Throwable friends	Normal	Fiendish	Grants Brickmin familiars that can be aimed and launched while nearby. There are 3 different Brickmin which have different effects and behaviors. Brickmin will be gained every 3 rooms, to a cap of 4.
Umbilical Geode	Fetal protection, geode bonus	Geode	Common	Chance to spawn a Gemini familiar when taking damage. Spawns a Little Steven familiar for the room when entering with half a heart of health or less. Geode Bonus: Chance of generating a Gemini familiar are increased, and Little Steven can spawn at only one heart of health or less.

Abyss Locusts

Abyss Locusts are small flies that resemble Blue Flies primarily spawned via absorbing items with Abyss. They fly behind the player and swarm forwards in the direction they fire in, damaging enemies on contact.

Fiend Folio adds in several unique Abyss Locusts for several items added in the mod when absorbed with Abyss.

Items	Locust Appearance	Effects
>3 Devilled Egg Evil Sticker Fetal Fiend Fiend Mix Fiend's Horn Imp Soda Lil Fiend Purple Putty The Devil's Harvest The Fiend Folio		Has a pink glow if Imp Soda was absorbed. If generated from Fiend Mix: Absorbing Fiend Mix grants 3 locusts. Deals 33% of Isaac's damage instead. Has a smaller hitbox. (50% of the usual) If generated from other items, will have no special effect.
A.V.G.M.		When flying into a wall or enemy, switches between white and dark grey. When switching colors, spawns a coin or random pickup. The number of times needed to spawn a reward increases each time, following the same rules as the A.V.G.M item itself.
Alpha Coin		No special effect.
Angelic Lyre		Absorbing Angelic Lyre gives 3 different colored locusts. The Blue Locust deals 33% of Isaac's damage. The Red Locust deals 100% of Isaac's damage, but moves 80% slower than other locusts. (20% move speed) The Yellow Locust deals 10% of Isaac's damage, but moves 100% faster than other locusts. (200% move speed)
Azurite Spindown		No special effect
Baby Crater Bridge Bombs Grappling Hook Modern Ouroboros Tea The Small Wood		If generated from The Small Wood: Deal 120% of Isaac's damage. Moves 10% slower than other locusts. (90% move speed) If generated from other items, will have no special effect.
Bacon Grease The Deluxe		Moves 80% slower than other locusts. (20% move speed)
Badump!		Absorbing Badump! grants 10 locusts. Deal 10% of Isaac's damage. Has 10% chance to charm enemies when hurting them.
Bag of Bobbies		Absorbing Bag of Bobbies grants 3 locusts. Deal 33% of Isaac's damage.
Batoomkling!		Absorbing Batoomkling! grants 10 locusts. Deal 10% of Isaac's damage. Has 10% chance to cause hemorrhaging when hurting enemies.
Bedtime Story		Absorbing Bedtime Story grants 3 locusts. Deal 33% of Isaac's damage. Have a chance to inflict sleeping when hurting enemies.
Bee Skin		Fires a stream of tears in a spinning pattern around itself when moving to attack These tears deal 10% of Isaac's damage.
Beginner's Luck		No special effect.
Birthday Gift		No special effect.
Black Moon		Enemies killed by the locust generate a red cross with an aura that hurts other enemies, identical to Black Moon's effect on Isaac's tears.
Bottle of Water		No special effect.
Box Top		No special effect.
Bzzt!		Absorbing Bzzt! grants 10 locusts. Deal 10% of Isaac's damage. 10% chance to apply confusion when hurting enemies.
Cherry Bomb		No special effect.
Chirumiru D3		If generated from Chirumiru: Deals 109% of Isaac's damage. If generated from other items, has no special effect.
Chomp Chomp! Glizzy		Deal 110% of Isaac's damage. Move 10% faster than other locusts. (110% move speed) Has a slightly bigger hitbox. (110% of usual size) If generated from Chomp Chomp!: Absorbing Chomp Chomp! grants 10 locusts. Deal 20% of Isaac's damage instead.
Clear Case		No special effect.
Clutch's Curse		No special effect.
Community Achievement		Deals 200% of Isaac's damage.
Contraband		Moves 10% slower than other locusts. (90% speed)
Cool Sunglasses		No special effect.
Corn Kernel Prank Cookie		If generated from Prank Cookie: Has a chance to apply any of the status effects Prank Cookie could apply. If generated from other items, will have no special effect.
Crazy Jackpot		Absorbing Crazy Jackpot grants 3 locusts. Deals 33% of Isaac's damage.
Crucifix		Enemies killed by the locust will generate the same stat boosting auras that Crucifix tears would.
D2		No special effect.
Dad's Dip Yick Heart		No special effect.
Dad's Postiche		No special effect.
Dad's Wallet		Absorbing Dad's Wallet grants 3 locusts. Deals 33% of Isaac's damage.
Dazzling Slot Golden Popsicle		No special effect.
Deadly Dose		No special effect.
Deimos Sanguine Hook		No special effect.
Devil's Dagger		Burns enemies on contact.
Devil's Umbrella		Spawns a thin line of yellow creep while moving. This creep deals 10% of Isaac's damage per tick.
Dice Bag		Absorbing Dice Bag grants 3 locusts. Deals 33% of Isaac's damage.
Dice Goblin Wimpy Bro		No special effect.
Dichromatic Butterfly		Homes in towards enemies.
Emoji Glasses		Fires a stream of tears in a circular pattern while moving to attack. These tears deal 10% of Isaac's damage.
Eternal D10 Eternal D12		No special effect.
Excelsior		No special effect.
Familiar Fly		Chance to apply charm when harming enemies.
Fiddle Cube		No special effects.
Fraudulent Fungus		Deals 120% of Isaac's damage.
Golden Frog Head Slippy's Guts Slippy's Heart		No special effect.
Golden Plum Flute		No special effects.
Golem's Orb		Moves twice as fast as other locusts. (200% move speed)
Golem's Rock Pet Rock		If generated from Pet Rock: Moves 90% slower than other locusts. (10% move speed) Has an extremely large hitbox (3 times the usual size), hitting enemies that don't visually touch its sprite. If generated from other items, will have no special effect.
Gorgoneion Store Whistle The Small Pipe		If Gorgoneion was absorbed: Deals 10% of Isaac's damage. Petrifies enemies hurt by this locust. If Store Whistle was absorbed: Killing an enemy with this locust has a 5% chance to spawn a random pickup for sale at a random price. If The Small Pipe was absorbed: Deals 110% of Isaac's damage.
Grabber		No special effects.
Greg The Egg		Moves 75% slower than other locusts. (25% move speed)
Griddle Corns Sack of Keys?		No special effect.
Horncob		When the Horncob locust kills an enemy, there is a chance to activate a random pill effect.
Host on Toast		Deals 115% of Isaac's damage. Moves 15% faster than other locusts. (115% move speed)
Hypno Ring		Chance to make enemies drowsy.
Infinity Volt		While moving to attack, a laser will connect Isaac and this locust. This laser deals 10% of Isaac's damage very rapidly.
IPad		Always moves downward, no matter which direction Isaac fires in.
Ka Ching! Penny Roll		If Penny Roll was absorbed: Grants 5 locusts. Deals 20% of Isaac's damage. If Ka Ching! was absorbed: Grants 10 locusts. Deals 10% of Isaac's damage. Has a 10% chance to apply Midas' Touch petrification.
Kalu's Severed Head		Has a chance to inflict enemies with petrification.
King Worm		No special effect.
Lawn Darts		Has a chance to inflict enemies with hemorrhaging.
Leftover Takeout		Deals 150% of Isaac's damage. Moves 15% faster than other locusts. (115% move speed) Has a high chance to show a random fortune when hitting an enemy.
Lemon Mishuh???		Deals 135% of Isaac's damage.
Loaded D6		If you have any other locusts when absorbing Loaded D6, the Loaded D6 locust will instead be replaced with any other locust you have.
Malice		Moves 100% faster than other locusts. (200% move speed) Leaves a line of slowing, black creep when moving to attack.
Maria's Smash Trophy		Deals additional knockback which scales with how much health an enemy has remaining. Makes Super Smash Bros. sound effects when hitting and killing enemies.
Mime Degree		Deals no damage to enemies. Blocks enemies.
Mom's Stockings		No special effect.
Mrs. Spooter		No special effect.
Musca		No special effect.
Nil Pasta		Has a 3.33% chance to glitch enemies.
Nugget Bombs		Currently bugged, absorbing Nugget Bombs creates a standard locust.
Nyx		Absorbing Nyx grants 3 locusts. Deals 66% of Isaac's damage.
Page of Virtues White Pepper		No special effect. If White Pepper was absorbed: Creates 5 locusts. Deals 20% of Isaac's damage. Has a chance to burn enemies.
Peppermint		Has a chance to slow enemies hit. Freezes enemies killed by this locust.
Perfectly Generic Object		No special effect.
Pet Peeve		No special effect.
Pinhead		Absorbing Pinhead grants 2 locusts. Deals 50% of Isaac's damage. Has a chance to apply sewn to hit enemies.
Pyromancy		Absorbing Pyromancy grants 3 locusts. Deals 33% of Isaac's damage.
Rat Poison Spare Ribs		If generated from Rat Poison: Poisons enemies. Has a green glow. If generated from Spare Ribs: Deals 33% of Isaac's damage. Creates 3 Spare Ribs projectile when hitting an enemy that deal 10% of Isaac's damage.
Risk's Reward		No special effect.
Robo-Baby 3.0		No special effect.
Rubber Bullets		Has a chance to bruise enemies.
Sibling Syl		Deals 105% of Isaac's damage.
Snow Globe		No special effect.
Strange Red Object		Deals 135% of Isaac's damage.
Telebombs		No special effect.
Time Itself		Has a chance to inflict enemies with multi-euclidean.
Toy Piano		Has a chance to doom enemies.
Wrong Warp		Has very erratic movement, often going in a completely different direction.
Your Eternal Reward		Deals 10% of Isaac's damage.